Hemoptysis
Basics
DESCRIPTION
- Hemoptysis is the expectoration of blood from the respiratory tract. The term comes from the Greek words haima, meaning blood, and ptysis, meaning spitting.
- Bleeding from the respiratory tract can range from blood-streaked sputum to massive hemoptysis from the lung. The amount and nature of bleeding should be characterized by taking a careful history.
- The source of bleeding can be anywhere in the respiratory tract, from the nose to the alveolus.
- Consequences of hemoptysis may include exsanguination, hypoxemia, and anemia or there may be none.
EPIDEMIOLOGY
Large series of pediatric patients with massive hemoptysis have not been described.
PATHOPHYSIOLOGY
- Related to the underlying pulmonary or cardiac disease
- Vascular origin of hemoptysis is from two locations:
- Pulmonary arteries: higher volume, lower pressure
- Bronchial arteries: lower volume, higher pressure
ETIOLOGY
- More common causes:
- Infection (pneumonia, bronchitis, viral illnesses)
- Bronchiectasis leading to erosion into a bronchial artery
- Trauma (pulmonary contusion, bronchoscopy, airway manipulation)
- Foreign body aspiration
- Cystic fibrosis
- Congenital heart disease with collateral vessels or pulmonary hypertension
- Tracheostomy-related complications
- Less common causes:
- Cavitary infections (e.g., tuberculosis, abscess, histoplasmosis)
- Factitious hemoptysis
- Congenital vascular or airway lesions (pulmonary arteriovenous malformation, hemangioma, bronchogenic cyst, pulmonary sequestration)
- Hemorrhagic diathesis, including anticoagulant therapy
- H-type tracheoesophageal fistula
- Pulmonary embolism
- Pulmonary hemosiderosis
- Tumors (teratomas, lymphomas)
- Immune mediated: Henoch-Schönlein purpura, Goodpasture syndrome, Anti-neutrophil cytoplasmic antibody (ANCA)-associated granulomatous vasculitis, polyarteritis nodosa, systemic lupus erythematosus, Heiner syndrome
- Sarcoidosis
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Citation
Cabana, Michael D., editor. "Hemoptysis." Select 5-Minute Pediatrics Topics, 7th ed., Wolters Kluwer Health, 2015. Medicine Central, im.unboundmedicine.com/medicine/view/Select-5-Minute-Pediatric-Consult/14019/all/Hemoptysis.
Hemoptysis. In: Cabana MDM, ed. Select 5-Minute Pediatrics Topics. Wolters Kluwer Health; 2015. https://im.unboundmedicine.com/medicine/view/Select-5-Minute-Pediatric-Consult/14019/all/Hemoptysis. Accessed December 10, 2024.
Hemoptysis. (2015). In Cabana, M. D. (Ed.), Select 5-Minute Pediatrics Topics (7th ed.). Wolters Kluwer Health. https://im.unboundmedicine.com/medicine/view/Select-5-Minute-Pediatric-Consult/14019/all/Hemoptysis
Hemoptysis [Internet]. In: Cabana MDM, editors. Select 5-Minute Pediatrics Topics. Wolters Kluwer Health; 2015. [cited 2024 December 10]. Available from: https://im.unboundmedicine.com/medicine/view/Select-5-Minute-Pediatric-Consult/14019/all/Hemoptysis.
* Article titles in AMA citation format should be in sentence-case
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