Select 5-Minute Pediatrics Topics
Leukocytosis
Basics
DESCRIPTION
Leukocytosis refers to a total white blood cell (WBC) count above the normal range for age.
RISK-FACTORS
- Very low-birth-weight neonates
- Immunodeficiencies or immunocompromised states
- Inflammatory disorders
- Autoimmune disorders
ALERT
Children with trisomy 21 (Down syndrome) have an increased risk of developing transient myeloproliferative disorder (TMD) or leukemoid reactions.
Children with trisomy 21 (Down syndrome) have an increased risk of developing transient myeloproliferative disorder (TMD) or leukemoid reactions.
PATHOPHYSIOLOGY
Leukocytosis results from increased marrow production, demargination, prolonged cell survival, and/or defective extravascularization in response to external stimuli or, less commonly, from an underlying marrow disorder.
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Citation
Cabana, Michael D., editor. "Leukocytosis." Select 5-Minute Pediatrics Topics, 7th ed., Wolters Kluwer Health, 2015. Medicine Central, im.unboundmedicine.com/medicine/view/Select-5-Minute-Pediatric-Consult/14015/all/Leukocytosis.
Leukocytosis. In: Cabana MDM, ed. Select 5-Minute Pediatrics Topics. Wolters Kluwer Health; 2015. https://im.unboundmedicine.com/medicine/view/Select-5-Minute-Pediatric-Consult/14015/all/Leukocytosis. Accessed December 26, 2024.
Leukocytosis. (2015). In Cabana, M. D. (Ed.), Select 5-Minute Pediatrics Topics (7th ed.). Wolters Kluwer Health. https://im.unboundmedicine.com/medicine/view/Select-5-Minute-Pediatric-Consult/14015/all/Leukocytosis
Leukocytosis [Internet]. In: Cabana MDM, editors. Select 5-Minute Pediatrics Topics. Wolters Kluwer Health; 2015. [cited 2024 December 26]. Available from: https://im.unboundmedicine.com/medicine/view/Select-5-Minute-Pediatric-Consult/14015/all/Leukocytosis.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Leukocytosis
ID - 14015
ED - Cabana,Michael D,
BT - Select 5-Minute Pediatrics Topics
UR - https://im.unboundmedicine.com/medicine/view/Select-5-Minute-Pediatric-Consult/14015/all/Leukocytosis
PB - Wolters Kluwer Health
ET - 7
DB - Medicine Central
DP - Unbound Medicine
ER -
