Catatonia or stiffness

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DDx

Severe stiffness or catatonia

  • Catatonic schizophrenia
  • Parkinson's disease
  • Catatonic syndrome due to other CNS causes, e.g., viral encephalitis, CNS bleed
  • Neuroleptic-induced catatonia
  • Seizure or status epilepticus
  • Neuroleptic malignant syndrome
  • Malignant hyperthermia
  • Tetany, e.g., hypocalcemia (usually distal muscles)
  • Dystonic reaction to neuroleptics, e.g., torticollis
  • Huntington's disease
  • Tetanus
  • Strychnine poisoning
  • Lethal catatonia
  • Stiff-person syndrome
  • Meningitis (stiff neck)
Mild stiffness
  • Arthritis, e.g., osteoarthritis, rheumatoid arthritis, pseudogout
  • Early parkinsonism
  • Fibromyalgia
  • Polymyalgia rheumatica

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DDx

Severe stiffness or catatonia

  • Catatonic schizophrenia
  • Parkinson's disease
  • Catatonic syndrome due to other CNS causes, e.g., viral encephalitis, CNS bleed
  • Neuroleptic-induced catatonia
  • Seizure or status epilepticus
  • Neuroleptic malignant syndrome
  • Malignant hyperthermia
  • Tetany, e.g., hypocalcemia (usually distal muscles)
  • Dystonic reaction to neuroleptics, e.g., torticollis
  • Huntington's disease
  • Tetanus
  • Strychnine poisoning
  • Lethal catatonia
  • Stiff-person syndrome
  • Meningitis (stiff neck)
Mild stiffness
  • Arthritis, e.g., osteoarthritis, rheumatoid arthritis, pseudogout
  • Early parkinsonism
  • Fibromyalgia
  • Polymyalgia rheumatica

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