Interstitial lung disease

Etiology

Drug-related

  • Amiodarone
  • Antibacterials (nitrofurantoin, sulfonamides)
  • Antineoplastics (bleomycin, cyclophosphamide, methotrexate, nitrosoureas)
  • Antirheumatics (gold salts, penicillamine)
  • Phenytoin
Environmental & occupational
  • Inorganic dust (asbestos, silica, hard metals, beryllium)
  • Organic dust or hypersensitivity pneumonitis (thermophilic actinomycetes, avian antigens, Aspergillus spp.)
  • Gases, fumes, vapors (chlorine, isocyanates, paraquat, sulfur dioxide)
  • Ionizing radiation
  • Talc (injection drug users)
Infections
  • Disseminated fungus (coccidioidomycosis, blastomycosis, histoplasmosis)
  • Disseminated mycobacteria
  • Pneumocystis jiroveci pneumonia
  • Viruses
Primary pulmonary syndromes
  • Idiopathic fibrosing interstitial pneumonia [idiopathic pulmonary fibrosis (IPF)]:
    • Acute interstitial pneumonia (AIP)
    • Desquamative interstitial pneumonia (DIP)
    • Nonspecific interstitial pneumonitis (NSIP)
    • Usual interstitial pneumonia (UIP)
    • Respiratory bronchiolitis-associated interstitial lung disease (RB-ILD)
  • Bronchiolitis obliterans-organizing pneumonia (BOOP)
Systemic disorders
  • Acute respiratory distress syndrome (ARDS)
  • Amyloidosis
  • Ankylosing spondylitis
  • Autoimmune disease: dermatomyositis, polymyositis, rheumatoid arthritis, systemic sclerosis (scleroderma), systemic lupus erythematosus
  • Chronic eosinophilic pneumonia
  • Goodpasture's syndrome
  • Idiopathic pulmonary hemosiderosis
  • Inflammatory bowel disease
  • Eosinophilic granuloma (Langerhans cell histiocytosis, histiocytosis X)
  • Lymphangitic carcinomatosis
  • Lymphangioleiomyomatosis (LAM)
  • Pulmonary edema
  • Pulmonary venous hypertension
  • Sarcoidosis
  • Wegener's granulomatosis

There's more to see -- the rest of this topic is available only to subscribers.

Last updated: December 1, 2014