Folic acid deficiency


  • Dietary deficiency
  • Decreased absorption: tropical sprue, drugs (phenytoin, sulfasalazine, trimethoprim-sulfamethoxazole)
  • Increased requirement: chronic hemolytic anemia, pregnancy, exfoliative skin disease
  • Loss: dialysis
  • Inhibition of reduction to active form: methotrexate

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Last updated: December 1, 2014