Abnormal premenopausal bleeding (increased or irregular)

DDx

  • Ovulation bleeding (spotting episode between menses)
  • Anovulatory cycle (dysfunctional uterine bleeding)
  • Polycystic ovary syndrome (type of anovulatory cycle)
  • Pregnancy
  • Ectopic pregnancy
  • Spontaneous abortion
  • Uterine leiomyomas (fibroids)
  • Endometrial polyp
  • Cervicitis or pelvic inflammatory disease
  • Adenomyosis (uterine endometriosis)
  • Cervical cancer
  • Cervical polyp
  • Endometrial hyperplasia
  • Endometrial cancer
  • Hypothyroidism
  • Hyperprolactinemia
  • Diabetes mellitus
  • Bleeding disorder, eg, von Willebrand’s disease
  • Hydatidiform mole

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Last updated: December 1, 2014