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Splenomegaly

Splenomegaly is a topic covered in the Diagnosaurus.

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DDx

  • Infections, eg, mononucleosis (Epstein-Barr virus), cytomegalovirus, acute HIV, endocarditis, histoplasmosis, malaria, schistosomiasis, leishmaniasis, filariasis
  • Chronic hemolytic anemia
  • Leukemia
  • Lymphoma
  • Extramedullary hematopoiesis, eg, myelofibrosis, marrow toxin
  • Polycythemia vera
  • Essential thrombocytosis
  • Cirrhosis or noncirrhotic portal hypertension
  • Congestive heart failure
  • Immune thrombocytopenias
  • Splenic vein thrombosis
  • Rheumatoid arthritis (Felty’s syndrome)
  • Systemic lupus erythematosus
  • Sarcoidosis
  • Wilson’s disease
  • Amyloidosis
  • Budd-Chiari syndrome
  • Gaucher disease
  • Niemann-Pick disease
  • Splenic cysts, hemangiomas, hamartomas, fibromas
  • Metastases, eg, melanoma
  • Eosinophilic granuloma (Langerhans cell histiocytosis, histiocytosis X)

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Last updated: December 1, 2014

Citation

Zeiger, Roni F.. "Splenomegaly." Diagnosaurus, 4th ed., McGraw-Hill Education, 2014. Medicine Central, im.unboundmedicine.com/medicine/view/Diagnosaurus/114508/all/Splenomegaly.
Zeiger RF. Splenomegaly. Diagnosaurus. 4th ed. McGraw-Hill Education; 2014. https://im.unboundmedicine.com/medicine/view/Diagnosaurus/114508/all/Splenomegaly. Accessed April 20, 2019.
Zeiger, R. F. (2014). Splenomegaly. In Diagnosaurus. Available from https://im.unboundmedicine.com/medicine/view/Diagnosaurus/114508/all/Splenomegaly
Zeiger RF. Splenomegaly [Internet]. In: Diagnosaurus. McGraw-Hill Education; 2014. [cited 2019 April 20]. Available from: https://im.unboundmedicine.com/medicine/view/Diagnosaurus/114508/all/Splenomegaly.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Splenomegaly ID - 114508 A1 - Zeiger,Roni F, Y1 - 2014/12/01/ BT - Diagnosaurus UR - https://im.unboundmedicine.com/medicine/view/Diagnosaurus/114508/all/Splenomegaly PB - McGraw-Hill Education ET - 4 DB - Medicine Central DP - Unbound Medicine ER -