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Infective endocarditis

Infective endocarditis is a topic covered in the Diagnosaurus.

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Native valve (non-IVDU)

  • Viridans streptococci (60%)
  • Staphylococcus aureus (20%)
  • Enterococci (5-10%)
  • Less common:
    • Other streptococci, eg, Streptococcus pneumoniae; group A Streptococcus; groups B, C, and G streptococci
    • HACEK organisms (gram-negative): Haemophilus aphrophilus, Haemophilus parainfluenzae, Actinobacillus actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens, Kingella kingae
    • Fungi

IVDU with native valve

  • Staphylococcus aureus (60%)
  • Enterococci
  • Streptococci
  • Gram-negative rods, eg, Pseudomonas, Serratia
  • Fungi, eg, Candida

Prosthetic valve

  • Early (< 2 months): Staphylococcus aureus, coagulase-negative Staphylococcus, gram-negatives, fungi
  • Late (>2 months): Like native valve plus coagulase-negative Staphylococcus

"Culture negative" endocarditis

  • Fungi
  • Q fever
  • Legionella
  • Psittacosis
  • Bartonella
  • Nutritionally deficient streptococci
  • Brucella
  • HACEK organisms
  • Anaerobes

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Last updated: January 13, 2015


Zeiger, Roni F.. "Infective Endocarditis." Diagnosaurus, 4th ed., McGraw-Hill Education, 2015. Medicine Central, im.unboundmedicine.com/medicine/view/Diagnosaurus/114092/all/Infective_endocarditis.
Zeiger RF. Infective endocarditis. Diagnosaurus. 4th ed. McGraw-Hill Education; 2015. https://im.unboundmedicine.com/medicine/view/Diagnosaurus/114092/all/Infective_endocarditis. Accessed April 19, 2019.
Zeiger, R. F. (2015). Infective endocarditis. In Diagnosaurus. Available from https://im.unboundmedicine.com/medicine/view/Diagnosaurus/114092/all/Infective_endocarditis
Zeiger RF. Infective Endocarditis [Internet]. In: Diagnosaurus. McGraw-Hill Education; 2015. [cited 2019 April 19]. Available from: https://im.unboundmedicine.com/medicine/view/Diagnosaurus/114092/all/Infective_endocarditis.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Infective endocarditis ID - 114092 A1 - Zeiger,Roni F, Y1 - 2015/01/13/ BT - Diagnosaurus UR - https://im.unboundmedicine.com/medicine/view/Diagnosaurus/114092/all/Infective_endocarditis PB - McGraw-Hill Education ET - 4 DB - Medicine Central DP - Unbound Medicine ER -