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thymus extract

General

Complementary/Alternative Medicine: This monograph describes a natural or herbal product that is not subject to FDA guidelines for medicines. Patients and clinicians are advised to read package labels carefully to ensure safe and efficacious use.

Pronunciation:
thahy-muhs


Trade Name(s)

  • thymomodulin
  • thymostimulin
  • thymus polypeptides

Ther. Class.
antiasthmatics
immune stimulants
allergy, cold and cough remedies

Common Uses

  • Respiratory infections.
  • Allergic rhinitis.
  • Asthma.
  • Food allergies.

Action

Thymus extract is derived from bovine thymus glands. It induces T-lymphocyte maturation, stimulates T-cell proliferation, enhances mature T-cell function and has indirect effects on macrophages and B-cell functions. It also reduces airway hyperresponsiveness to methacholine in atopic asthma patients.

Therapeutic Effect(s):

  • Improved immune function.
  • Reduced acute asthma attacks.

Pharmacokinetics

Absorption: Unknown

Distribution: Unknown

Metabolism and Excretion: Unknown

Half-life: Unknown

TIME/ACTION PROFILE

ONSETPEAKDURATION
POunknownunknownunknown

Contraindication/Precautions

Contraindicated in:

  • Hypersensitivity.
  • Immunocompromised patients should only use products that are certified pathogen-free to reduce the risk of infection from diseased animal parts.

Use Cautiously in:

Pregnancy and lactation.

Adverse Reactions/Side Effects

Misc: Potential risk of contamination from diseased animal parts.

* CAPITALS indicate life-threatening.
Underline indicate most frequent.

Interactions

Natural Drug Interaction

Avoid use with immunosuppressants unless products are certified pathogen-free.

Natural-Natural:

None.

Route/Dosage

PO: (Adults) 750 mg/day of crude thymus polypeptide fraction or 120 mg/day of pure thymus polypeptides (thymomodulin).

Availability

Capsules

Assessment

  • Assess symptoms of cold or allergies related to the purpose thymus extract is being taken.

Potential Diagnoses

  • Risk for infection (Indications)

Implementation

  • PO: Administer as recommended.

Patient/Family Teaching

  • Discuss with patient purpose for taking thymus extract.
  • Advise patient to notify health care professional of all Rx or OTC medications, vitamins, or herbal products being taken and to consult with health care professional before taking other medications.
  • Advise female patient to notify health care professional if pregnancy is planned or suspected or if breastfeeding.

Evaluation/Desired Outcomes

Improvement in symptoms of cold or allergic rhinitis.

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Citation

Quiring, Courtney, et al. "Thymus Extract." Davis's Drug Guide, 16th ed., F.A. Davis Company, 2019. Medicine Central, im.unboundmedicine.com/medicine/view/Davis-Drug-Guide/110116/all/thymus_extract.
Quiring C, Sanoski CA, Vallerand AH. Thymus extract. Davis's Drug Guide. 16th ed. F.A. Davis Company; 2019. https://im.unboundmedicine.com/medicine/view/Davis-Drug-Guide/110116/all/thymus_extract. Accessed April 21, 2019.
Quiring, C., Sanoski, C. A., & Vallerand, A. H. (2019). Thymus extract. In Davis's Drug Guide. Available from https://im.unboundmedicine.com/medicine/view/Davis-Drug-Guide/110116/all/thymus_extract
Quiring C, Sanoski CA, Vallerand AH. Thymus Extract [Internet]. In: Davis's Drug Guide. F.A. Davis Company; 2019. [cited 2019 April 21]. Available from: https://im.unboundmedicine.com/medicine/view/Davis-Drug-Guide/110116/all/thymus_extract.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - thymus extract ID - 110116 A1 - Quiring,Courtney, AU - Sanoski,Cynthia A, AU - Vallerand,April Hazard, BT - Davis's Drug Guide UR - https://im.unboundmedicine.com/medicine/view/Davis-Drug-Guide/110116/all/thymus_extract PB - F.A. Davis Company ET - 16 DB - Medicine Central DP - Unbound Medicine ER -