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Pityriasis Rosea

Pityriasis Rosea is a topic covered in the 5-Minute Clinical Consult.

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Basics

Description

  • An idiopathic, self-limited skin eruption characterized by widespread papulosquamous lesions
  • System(s) affected: skin/exocrine

Pediatric Considerations
Face and distal extremities are more often involved in children, and lesions may be more papular.

Epidemiology

  • Predominant age: 10 to 35 years but occurs in all age groups
  • Predominant sex: male = female
    • Some studies have shown a slight female preponderance.
  • No racial predominance

Incidence
Relatively common, but exact frequency is unknown; one study noted 170 out of 100,000 yearly incidence (1).

Etiology and Pathophysiology

  • Unknown; may be a viral agent or an autoimmune disorder. Several studies have implicated the human herpesviruses (HHV), most commonly HHV-7, but other research has not confirmed this association. Case reports have also suggested an association with novel influenza A (H1N1) infection.
  • A similar rash has been reported with several drugs including gold injections, captopril, interferon, omeprazole, and bismuth.

Genetics
<5% of those affected give a positive family history.

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Citation

Stephens, Mark B., et al., editors. "Pityriasis Rosea." 5-Minute Clinical Consult, 27th ed., Wolters Kluwer, 2019. Medicine Central, im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/816371/all/Pityriasis_Rosea.
Pityriasis Rosea. In: Stephens MB, Golding J, Baldor RA, et al, eds. 5-Minute Clinical Consult. 27th ed. Wolters Kluwer; 2019. https://im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/816371/all/Pityriasis_Rosea. Accessed April 19, 2019.
Pityriasis Rosea. (2019). In Stephens, M. B., Golding, J., Baldor, R. A., & Domino, F. J. (Eds.), 5-Minute Clinical Consult. Available from https://im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/816371/all/Pityriasis_Rosea
Pityriasis Rosea [Internet]. In: Stephens MB, Golding J, Baldor RA, Domino FJ, editors. 5-Minute Clinical Consult. Wolters Kluwer; 2019. [cited 2019 April 19]. Available from: https://im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/816371/all/Pityriasis_Rosea.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Pityriasis Rosea ID - 816371 ED - Stephens,Mark B, ED - Golding,Jeremy, ED - Baldor,Robert A, ED - Domino,Frank J, BT - 5-Minute Clinical Consult, Updating UR - https://im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/816371/all/Pityriasis_Rosea PB - Wolters Kluwer ET - 27 DB - Medicine Central DP - Unbound Medicine ER -