Arthritis, Rheumatoid (RA)
- Rheumatoid arthritis (RA) is a chronic inflammatory disease primarily causing synovial inflammation leading to the destruction of bone and cartilage (1).
- Classification: based on the duration of disease (1)
- Early: ≤6 months
- Established: ≥6 months
- Based on the disease activity: low, moderate, high, or remission
Annual incidence: United States is approximately 40/100,000 persons.
- Prevalence: 0.5–1% of the general population worldwide
- Female:male, 2:1
Etiology and Pathophysiology
The cause remains uncertain; often precipitated by stress or insult (e.g., infection, smoking, trauma)
Females at a younger age (5th to 6th decade), first- and second-degree relative), North American regions, Native Americans, smoking, obesity, lower socioeconomic status infections
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Domino, Frank J., et al., editors. "Arthritis, Rheumatoid (RA)." 5-Minute Clinical Consult, 27th ed., Wolters Kluwer, 2020. Medicine Central, im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/1688888/all/Arthritis_Rheumatoid__RA_.
Arthritis, Rheumatoid (RA). In: Domino FJF, Baldor RAR, Golding JJ, et al, eds. 5-Minute Clinical Consult. Wolters Kluwer; 2020. https://im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/1688888/all/Arthritis_Rheumatoid__RA_. Accessed June 4, 2023.
Arthritis, Rheumatoid (RA). (2020). In Domino, F. J., Baldor, R. A., Golding, J., & Stephens, M. B. (Eds.), 5-Minute Clinical Consult (27th ed.). Wolters Kluwer. https://im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/1688888/all/Arthritis_Rheumatoid__RA_
Arthritis, Rheumatoid (RA) [Internet]. In: Domino FJF, Baldor RAR, Golding JJ, Stephens MBM, editors. 5-Minute Clinical Consult. Wolters Kluwer; 2020. [cited 2023 June 04]. Available from: https://im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/1688888/all/Arthritis_Rheumatoid__RA_.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Arthritis, Rheumatoid (RA) ID - 1688888 ED - Domino,Frank J, ED - Baldor,Robert A, ED - Golding,Jeremy, ED - Stephens,Mark B, BT - 5-Minute Clinical Consult, Updating UR - https://im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/1688888/all/Arthritis_Rheumatoid__RA_ PB - Wolters Kluwer ET - 27 DB - Medicine Central DP - Unbound Medicine ER -