Costochondritis
BASICS
DESCRIPTION
- Anterior chest wall pain and tenderness of the costochondral and costosternal regions, most often affecting the 2nd to the 5th costal cartilages
- System(s) affected: musculoskeletal
- Synonym(s): costosternal syndrome; parasternal chondrodynia; anterior chest wall syndrome
EPIDEMIOLOGY
- Predominant age: 40 to 50 years
- Predominant gender: female sex assigned at birth
Incidence
- Around one-third of noncardiac chest pain visits in emergency departments are of musculoskeletal origin.
- Around 10% of chest wall pain in primary care setting diagnosed with costochondritis.
ETIOLOGY AND PATHOPHYSIOLOGY
Although not fully understood, inflammation can be caused by pulling from adjoining muscles at costochondral or costosternal regions.
RISK FACTORS
- Unusual physical activity or upper extremity overuse
- Recent trauma (including motor vehicle accident, domestic violence) or new-onset physical activity
- Recent upper respiratory infection (URI) with coughing
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Citation
Domino, Frank J., et al., editors. "Costochondritis." 5-Minute Clinical Consult, 34th ed., Wolters Kluwer, 2026. Medicine Central, im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/1688709/1.1/Costochondritis.
Costochondritis. In: Domino FJF, Baldor RAR, Golding JJ, et al, eds. 5-Minute Clinical Consult. Wolters Kluwer; 2026. https://im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/1688709/1.1/Costochondritis. Accessed July 17, 2025.
Costochondritis. (2026). In Domino, F. J., Baldor, R. A., Golding, J., & Stephens, M. B. (Eds.), 5-Minute Clinical Consult (34th ed.). Wolters Kluwer. https://im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/1688709/1.1/Costochondritis
Costochondritis [Internet]. In: Domino FJF, Baldor RAR, Golding JJ, Stephens MBM, editors. 5-Minute Clinical Consult. Wolters Kluwer; 2026. [cited 2025 July 17]. Available from: https://im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/1688709/1.1/Costochondritis.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Costochondritis
ID - 1688709
ED - Domino,Frank J,
ED - Baldor,Robert A,
ED - Golding,Jeremy,
ED - Stephens,Mark B,
BT - 5-Minute Clinical Consult, Updating
UR - https://im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/1688709/1.1/Costochondritis
PB - Wolters Kluwer
ET - 34
DB - Medicine Central
DP - Unbound Medicine
ER -