Pilonidal Disease

Descriptive text is not available for this image Basics

Description

  • Pilonidal disease results from an abscess, or sinus tract, in the upper part of the natal (gluteal) cleft.
  • Synonym(s): jeep disease

Epidemiology

Incidence

  • 16 to 26/100,000 per year
  • Predominant sex: male > female (3 to 4:1)
  • Predominant age: 2nd to 3rd decade, rare in age >45 years
  • Ethnic/racial consideration: White > Black > Asian

Prevalence

Surgical procedures show male:female ratio of 4:1, yet incidence data are 10:1.

Etiology and Pathophysiology

Pilonidal means “nest of hair”; hair in the natal cleft allows hair to be drawn into the deeper tissues via negative pressure caused by movement of the buttocks (50%); follicular occlusion from stretching and blocking of pores with debris (50%) creating a pilonidal cyst

  • Inflammation of SC gluteal tissues with secondary infection and sinus tract formation
  • Polymicrobial, likely from enteric pathogens given proximity to anorectal contamination

Genetics

  • Congenital dimple in the natal cleft/spina bifida occulta
  • Follicular-occluding tetrad: acne conglobata, dissecting cellulitis, hidradenitis suppurativa, pilonidal

Risk Factors

  • Sedentary/prolonged sitting
  • Excessive body hair
  • Obesity/increased sacrococcygeal fold thickness
  • Congenital natal dimple
  • Trauma to coccyx

General Prevention

  • Weight loss
  • Trim hair in/around gluteal cleft weekly.
  • Hygiene
  • Ingrown hair prevention/follicle unblocking

Commonly Associated Conditions

Obesity, hirsutism, and sedentary lifestyle

Descriptive text is not available for this image Diagnosis

History

Three distinct clinical presentations

  • Asymptomatic: painless cyst or sinus at the top of the gluteal cleft, fever is rare
  • Acute abscess: severe pain, swelling, discharge from the top of the gluteal cleft that may or may not have drained spontaneously
  • Chronic abscess: persistent drainage from a sinus tract at the top of the gluteal cleft

Physical Exam

  • Common: inflamed cystic mass at the top of the gluteal cleft with limited surrounding erythema ± drainage or a sinus tract
  • Inflamed sinus accompanied by ≥1 pits with or without hair debris
  • Less common: significant cellulitis of the surrounding tissues near the gluteal cleft

Differential Diagnosis

  • Furunculosis or folliculitis
  • Hidradenitis suppurativa
  • Anal fistula
  • Perirectal abscess
  • Crohn disease

Diagnostic Tests & Interpretation

Generally, no tests are needed because it can be diagnosed clinically.

Initial Tests (lab, imaging)

  • Consider CBC and wound culture but generally not necessary for less severe infections.
  • Ultrasound or MRI might be considered to differentiate between perirectal abscess and pilonidal disease.

Diagnostic Procedures/Other

Wound culture if infection is suspected

Descriptive text is not available for this image Treatment

General Measures

  • Shave hair area; remove hair from crypts weekly (1).
  • Asymptomatic disease does not need surgical treatment.
  • Lifestyle modification with regular exercise and weight loss (1),(2),(3)

Medication

  • Antibiotics are not indicated unless there is significant cellulitis.
  • If antibiotics are needed, a culture to guide therapy might be useful.
  • Cefazolin plus metronidazole or amoxicillin-clavulanate are often used empirically if cellulitis is suspected.
  • For penicillin allergy, may consider clindamycin plus a fluoroquinolone.

Issues for Referral

  • Patients who cannot comply with frequent dressing changes required after incision and drainage (I&D)
  • Patients who have recurrence after I&D
  • Patients who have complex disease with multiple sinus tracts

Additional Therapies

  • I&D with only enough packing to allow the cyst to drain; overpacking not indicated
  • Antibiotics only if significant cellulitis and abscess; temporizing, not curative
  • Negative pressure wound therapy
  • Laser epilation of hair in the gluteal fold
  • Phenol infusion treatment can be used especially for recurring disease.

Surgery/Other Procedures

  • Several surgical techniques have proposed with limited data on superiority of one over another.
  • Six levels of care based on severity or recurrence of disease; recent innovations in technique are aimed at expediting healing and minimizing recurrence.
    • I&D, remove hair, curette granulation tissue (3)[C]
    • Excision of midline “pits” allows drainage of lateral sinus tracts (pit picking) (1),(2),(4)[A].
    • Pilonidal cystotomy: Insert probe into sinus tract, excise overlying skin, and close wound.
    • Marsupialization: Excise overlying skin and roof of cyst, and suture skin edges to cyst floor (3).
    • Excision: use of flap closure; no clear benefit for open healing over surgical closure
    • Off-midline surgical excision (cleft lift or modified Karydakis procedure): A systematic review showed a clear benefit in favor of off-midline rather than midline wound closure. When closure of pilonidal sinuses is the desired surgical option, off-midline closure should be the standard management (2),(3),(4)[A].
    • Endoscopic pilonidal sinus treatment (EPSiT): minimally invasive procedure
  • Endoscopic treatment such as EPSiT
  • Fibrin glue in conjunction with some type of minimally excision

Admission, Inpatient, and Nursing Considerations

  • Severe cellulitis
  • Large area excision

Descriptive text is not available for this image Ongoing Care

Follow-up Recommendations

  • Frequent dressing changes required after I&D
  • Follow-up wound checks to assess for recurrence

Patient Monitoring

Monitor for fever; more extensive cellulitis

Patient Education

  • Wash area briskly with washcloth daily.
  • Shave the area weekly.
  • Remove any embedded hair from the crypt.
  • Avoid prolonged sitting.

Prognosis

  • Simple I&D has a 55% failure rate; median time to healing is 5 weeks.
  • More extensive surgical excisions involve hospital stays and longer time to heal.

Complications

Malignant degeneration is a rare complication of untreated chronic pilonidal disease.

Authors

Tam T. Nguyen, MD

References

  1. Gil LA, Deans KJ, Minneci PC. Management of pilonidal disease: a review. JAMA Surg. 2023;158(8):875–883.  [PMID:37256592]
  2. Johnson EK, Vogel JD, Cowan ML, et al. The American Society of Colon and Rectal Surgeons’ clinical practice guidelines for the management of pilonidal disease. Dis Colon Rectum. 2019;62(2):146–157.  [PMID:30640830]
  3. Humphries AE, Duncan JE. Evaluation and management of pilonidal disease. Surg Clin North Am. 2010;90(1):113–124.  [PMID:20109636]
  4. Bi S, Sun K, Chen S, et al. Surgical procedures in the pilonidal sinus disease: a systematic review and network meta-analysis. Sci Rep. 2020;10(1):13720.  [PMID:32792519]

Descriptive text is not available for this image Codes

ICD-10

  • L05.91 Pilonidal cyst without abscess
  • L05.92 Pilonidal sinus without abscess
  • L05.01 Pilonidal cyst with abscess
  • L05.02 Pilonidal sinus with abscess

SNOMED

  • 432863009 pilonidal disease (disorder)
  • 47639008 cyst - pilonidal (disorder)
  • 85224001 pilonidal cyst with abscess (disorder)
  • 311453002 Pilonidal sinus of natal cleft
  • 76545008 pilonidal cyst without abscess (disorder)
  • 200715006 Pilonidal sinus without abscess
  • 431709001 Pilonidal abscess of natal cleft

Clinical Pearls

  • Avoid prolonged sitting.
  • Lose weight.
  • Trim hair in gluteal cleft weekly.
  • Refer recurring infections for more definitive surgical management.

Last Updated: 2027

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