Pilonidal Disease
Basics
Description
- Pilonidal disease results from an abscess, or sinus tract, in the upper part of the natal (gluteal) cleft.
- Synonym(s): jeep disease
Epidemiology
Incidence
- 16 to 26/100,000 per year
- Predominant sex: male > female (3 to 4:1)
- Predominant age: 2nd to 3rd decade, rare in age >45 years
- Ethnic/racial consideration: White > Black > Asian
Prevalence
Surgical procedures show male:female ratio of 4:1, yet incidence data are 10:1.
Etiology and Pathophysiology
Pilonidal means “nest of hair”; hair in the natal cleft allows hair to be drawn into the deeper tissues via negative pressure caused by movement of the buttocks (50%); follicular occlusion from stretching and blocking of pores with debris (50%) creating a pilonidal cyst
- Inflammation of SC gluteal tissues with secondary infection and sinus tract formation
- Polymicrobial, likely from enteric pathogens given proximity to anorectal contamination
Genetics
- Congenital dimple in the natal cleft/spina bifida occulta
- Follicular-occluding tetrad: acne conglobata, dissecting cellulitis, hidradenitis suppurativa, pilonidal
Risk Factors
- Sedentary/prolonged sitting
- Excessive body hair
- Obesity/increased sacrococcygeal fold thickness
- Congenital natal dimple
- Trauma to coccyx
General Prevention
- Weight loss
- Trim hair in/around gluteal cleft weekly.
- Hygiene
- Ingrown hair prevention/follicle unblocking
Commonly Associated Conditions
Obesity, hirsutism, and sedentary lifestyle
Diagnosis
History
Three distinct clinical presentations
- Asymptomatic: painless cyst or sinus at the top of the gluteal cleft, fever is rare
- Acute abscess: severe pain, swelling, discharge from the top of the gluteal cleft that may or may not have drained spontaneously
- Chronic abscess: persistent drainage from a sinus tract at the top of the gluteal cleft
Physical Exam
- Common: inflamed cystic mass at the top of the gluteal cleft with limited surrounding erythema ± drainage or a sinus tract
- Inflamed sinus accompanied by ≥1 pits with or without hair debris
- Less common: significant cellulitis of the surrounding tissues near the gluteal cleft
Differential Diagnosis
- Furunculosis or folliculitis
- Hidradenitis suppurativa
- Anal fistula
- Perirectal abscess
- Crohn disease
Diagnostic Tests & Interpretation
Generally, no tests are needed because it can be diagnosed clinically.
Initial Tests (lab, imaging)
- Consider CBC and wound culture but generally not necessary for less severe infections.
- Ultrasound or MRI might be considered to differentiate between perirectal abscess and pilonidal disease.
Diagnostic Procedures/Other
Wound culture if infection is suspected
Treatment
General Measures
Medication
- Antibiotics are not indicated unless there is significant cellulitis.
- If antibiotics are needed, a culture to guide therapy might be useful.
- Cefazolin plus metronidazole or amoxicillin-clavulanate are often used empirically if cellulitis is suspected.
- For penicillin allergy, may consider clindamycin plus a fluoroquinolone.
Issues for Referral
- Patients who cannot comply with frequent dressing changes required after incision and drainage (I&D)
- Patients who have recurrence after I&D
- Patients who have complex disease with multiple sinus tracts
Additional Therapies
- I&D with only enough packing to allow the cyst to drain; overpacking not indicated
- Antibiotics only if significant cellulitis and abscess; temporizing, not curative
- Negative pressure wound therapy
- Laser epilation of hair in the gluteal fold
- Phenol infusion treatment can be used especially for recurring disease.
Surgery/Other Procedures
- Several surgical techniques have proposed with limited data on superiority of one over another.
- Six levels of care based on severity or recurrence of disease; recent innovations in technique are aimed at expediting healing and minimizing recurrence.
- I&D, remove hair, curette granulation tissue (3)[]
- Pilonidal cystotomy: Insert probe into sinus tract, excise overlying skin, and close wound.
- Marsupialization: Excise overlying skin and roof of cyst, and suture skin edges to cyst floor (3).
- Excision: use of flap closure; no clear benefit for open healing over surgical closure
- Off-midline surgical excision (cleft lift or modified Karydakis procedure): A systematic review showed a clear benefit in favor of off-midline rather than midline wound closure. When closure of pilonidal sinuses is the desired surgical option, off-midline closure should be the standard management (2),(3),(4)[].
- Endoscopic pilonidal sinus treatment (EPSiT): minimally invasive procedure
- Endoscopic treatment such as EPSiT
- Fibrin glue in conjunction with some type of minimally excision
Admission, Inpatient, and Nursing Considerations
- Severe cellulitis
- Large area excision
Ongoing Care
Follow-up Recommendations
- Frequent dressing changes required after I&D
- Follow-up wound checks to assess for recurrence
Patient Monitoring
Monitor for fever; more extensive cellulitis
Patient Education
- Wash area briskly with washcloth daily.
- Shave the area weekly.
- Remove any embedded hair from the crypt.
- Avoid prolonged sitting.
Prognosis
- Simple I&D has a 55% failure rate; median time to healing is 5 weeks.
- More extensive surgical excisions involve hospital stays and longer time to heal.
Complications
Malignant degeneration is a rare complication of untreated chronic pilonidal disease.
Authors
Tam T. Nguyen, MD
References
- , , . Management of pilonidal disease: a review. JAMA Surg. 2023;158(8):875–883. [PMID:37256592]
- , , , et al. The American Society of Colon and Rectal Surgeons’ clinical practice guidelines for the management of pilonidal disease. Dis Colon Rectum. 2019;62(2):146–157. [PMID:30640830]
- , . Evaluation and management of pilonidal disease. Surg Clin North Am. 2010;90(1):113–124. [PMID:20109636]
- , , , et al. Surgical procedures in the pilonidal sinus disease: a systematic review and network meta-analysis. Sci Rep. 2020;10(1):13720. [PMID:32792519]
Codes
ICD-10
- L05.91 Pilonidal cyst without abscess
- L05.92 Pilonidal sinus without abscess
- L05.01 Pilonidal cyst with abscess
- L05.02 Pilonidal sinus with abscess
SNOMED
- 432863009 pilonidal disease (disorder)
- 47639008 cyst - pilonidal (disorder)
- 85224001 pilonidal cyst with abscess (disorder)
- 311453002 Pilonidal sinus of natal cleft
- 76545008 pilonidal cyst without abscess (disorder)
- 200715006 Pilonidal sinus without abscess
- 431709001 Pilonidal abscess of natal cleft
Clinical Pearls
- Avoid prolonged sitting.
- Lose weight.
- Trim hair in gluteal cleft weekly.
- Refer recurring infections for more definitive surgical management.
Last Updated: 2027
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