Pilonidal Disease
Basics
Description
- Pilonidal disease results from an abscess, or sinus tract, in the upper part of the natal (gluteal) cleft.
- Synonym(s): jeep disease
Epidemiology
Incidence
- 16 to 26/100,000 per year
- Predominant sex: male > female (3 to 4:1)
- Predominant age: 2nd to 3rd decade, rare in age >45 years
- Ethnic consideration: whites > blacks > Asians
Prevalence
Surgical procedures show male:female ratio of 4:1, yet incidence data are 10:1.
Etiology and Pathophysiology
Pilonidal means “nest of hair”; hair in the natal cleft allows hair to be drawn into the deeper tissues via negative pressure caused by movement of the buttocks (50%); follicular occlusion from stretching and blocking of pores with debris (50%) creating a pilonidal cyst
- Inflammation of SC gluteal tissues with secondary infection and sinus tract formation
- Polymicrobial, likely from enteric pathogens given proximity to anorectal contamination
Genetics
- Congenital dimple in the natal cleft/spina bifida occulta
- Follicular-occluding tetrad: acne conglobata, dissecting cellulitis, hidradenitis suppurativa, pilonidal
Risk Factors
- Sedentary/prolonged sitting
- Excessive body hair
- Obesity/increased sacrococcygeal fold thickness
- Congenital natal dimple
- Trauma to coccyx
General Prevention
- Weight loss
- Trim hair in/around gluteal cleft weekly.
- Hygiene
- Ingrown hair prevention/follicle unblocking
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Citation
Domino, Frank J., et al., editors. "Pilonidal Disease." 5-Minute Clinical Consult, 33rd ed., Wolters Kluwer, 2025. Medicine Central, im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/1688635/all/Pilonidal_Disease.
Pilonidal Disease. In: Domino FJF, Baldor RAR, Golding JJ, et al, eds. 5-Minute Clinical Consult. Wolters Kluwer; 2025. https://im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/1688635/all/Pilonidal_Disease. Accessed December 17, 2024.
Pilonidal Disease. (2025). In Domino, F. J., Baldor, R. A., Golding, J., & Stephens, M. B. (Eds.), 5-Minute Clinical Consult (33rd ed.). Wolters Kluwer. https://im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/1688635/all/Pilonidal_Disease
Pilonidal Disease [Internet]. In: Domino FJF, Baldor RAR, Golding JJ, Stephens MBM, editors. 5-Minute Clinical Consult. Wolters Kluwer; 2025. [cited 2024 December 17]. Available from: https://im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/1688635/all/Pilonidal_Disease.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Pilonidal Disease
ID - 1688635
ED - Domino,Frank J,
ED - Baldor,Robert A,
ED - Golding,Jeremy,
ED - Stephens,Mark B,
BT - 5-Minute Clinical Consult, Updating
UR - https://im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/1688635/all/Pilonidal_Disease
PB - Wolters Kluwer
ET - 33
DB - Medicine Central
DP - Unbound Medicine
ER -