Pilonidal Disease
BASICS
DESCRIPTION
- Pilonidal disease results from an abscess, or sinus tract, in the upper part of the natal (gluteal) cleft.
- Synonym(s): jeep disease
EPIDEMIOLOGY
Incidence
- 16 to 26/100,000 per year
- Predominant sex: male > female (3 to 4:1)
- Predominant age: 2nd to 3rd decade, rare in age >45 years
- Ethnic consideration: whites > blacks > Asians
Prevalence
Surgical procedures show male:female ratio of 4:1, yet incidence data are 10:1.
ETIOLOGY AND PATHOPHYSIOLOGY
Pilonidal means “nest of hair”; hair in the natal cleft allows hair to be drawn into the deeper tissues via negative pressure caused by movement of the buttocks (50%); follicular occlusion from stretching and blocking of pores with debris (50%) creating a pilonidal cyst
- Inflammation of SC gluteal tissues with secondary infection and sinus tract formation
- Polymicrobial, likely from enteric pathogens given proximity to anorectal contamination
Genetics
- Congenital dimple in the natal cleft/spina bifida occulta
- Follicular-occluding tetrad: acne conglobata, dissecting cellulitis, hidradenitis suppurativa, pilonidal
RISK FACTORS
- Sedentary/prolonged sitting
- Excessive body hair
- Obesity/increased sacrococcygeal fold thickness
- Congenital natal dimple
- Trauma to coccyx
GENERAL PREVENTION
- Weight loss
- Trim hair in/around gluteal cleft weekly.
- Hygiene
- Ingrown hair prevention/follicle unblocking
DIAGNOSIS
HISTORY
Three distinct clinical presentations
- Asymptomatic: painless cyst or sinus at the top of the gluteal cleft; fever is rare.
- Acute abscess: severe pain, swelling, and/or discharge from the top of the gluteal cleft that may or may not have drained spontaneously
- Chronic abscess: persistent drainage from a sinus tract at the top of the gluteal cleft
PHYSICAL EXAM
- Common: inflamed cystic mass at the top of the gluteal cleft with limited surrounding erythema ± drainage or a sinus tract
- Inflamed sinus accompanied with one or more pits with or without hair debris
- Less common: significant cellulitis of the surrounding tissues near the gluteal cleft
DIFFERENTIAL DIAGNOSIS
- Furunculosis or folliculitis
- Hidradenitis suppurativa
- Anal fistula
- Perirectal abscess
- Crohn disease
DIAGNOSTIC TESTS & INTERPRETATION
Generally, no tests are needed since it can be diagnosed clinically.
Initial Tests (lab, imaging)
- Consider CBC and wound culture but generally not necessary for less severe infections.
- Ultrasound or MRI might be considered to differentiate between perirectal abscess and pilonidal disease.
Follow-Up Tests & Special Considerations
None
Diagnostic Procedures/Other
Wound culture if infection is suspected
TREATMENT
GENERAL MEASURES
- Shave hair area; remove hair from crypts weekly.
- Asymptomatic disease does not need surgical treatment.
MEDICATION
- Antibiotics are not indicated unless there is a significant cellulitis (1).
- If antibiotics are needed, a culture to direct therapy might be useful.
- Cefazolin plus metronidazole or amoxicillin-clavulanate are often used empirically if cellulitis is suspected.
ISSUES FOR REFERRAL
- Patients who cannot comply with frequent dressing changes required after incision and drainage (I&D)
- Patients who have recurrence after I&D
- Patients who have complex disease with multiple sinus tracts
ADDITIONAL THERAPIES
- I&D with only enough packing to allow the cyst to drain; overpacking is not indicated.
- Antibiotics only if significant cellulitis and abscess; temporizing, not curative
- Negative pressure wound therapy
- Laser epilation of hair in the gluteal fold (2)[ ]
- Phenol infusion treatment can be used, especially for recurring disease.
SURGERY/OTHER PROCEDURES
- Several surgical techniques have proposed with limited data on superiority of one over another.
- Six levels of care based on severity or recurrence of disease; recent innovations in technique are aimed at expediting healing and minimizing recurrence.
- I&D, remove hair, curette granulation tissue (3)[ ]
- Excision of midline “pits” allows drainage of lateral sinus tracts (pit picking).
- Pilonidal cystotomy: Insert probe into sinus tract, excise overlying skin, and close wound (4)[ ].
- Excision: use of flap closure; no clear benefit for open healing over surgical closure
- Off-midline surgical excision (cleft lift or modified Karydakis procedure): A systematic review showed a clear benefit in favor of off-midline rather than midline wound closure. When closure of pilonidal sinuses is the desired surgical option, off-midline closure should be the standard management (3)[ ].
- Endoscopic pilonidal sinus treatment (EPSiT): minimally invasive procedure (6)
- Endoscopic treatment such as EPSiT (endoscopic pilonidal sinus surgery)
- Fibrin glue in conjunction with some type of minimally excision
ADMISSION, INPATIENT, AND NURSING CONSIDERATIONS
- Severe cellulitis
- Large area excision
ONGOING CARE
FOLLOW-UP RECOMMENDATIONS
- Frequent dressing changes are required after I&D.
- Follow-up wound checks to assess for recurrence
Patient Monitoring
Monitor for fever; more extensive cellulitis
PATIENT EDUCATION
- Wash area briskly with washcloth daily.
- Shave the area weekly.
- Remove any embedded hair from the crypt.
- Avoid prolonged sitting.
PROGNOSIS
- Simple I&D has a 55% failure rate; median time to healing is 5 weeks.
- More extensive surgical excisions involve hospital stays and longer time to heal.
COMPLICATIONS
Malignant degeneration is a rare complication of untreated chronic pilonidal disease.
Authors
Tam T. Nguyen, MD
REFERENCES
- et al. Antimicrobials as an adjunct to pilonidal disease surgery: a systematic review of the literature. Eur J Clin Microbiol Infect Dis. 2013;32(7):851–858. [PMID:23380885] , , ,
- [PMID:22426275] , , . Pilonidal disease: time to reevaluate a common pain in the rear! Dis Colon Rectum. 2012;55(4):491–493.
- [PMID:20109636] , . Evaluation and management of pilonidal disease. Surg Clin North Am. 2010;90(1):113–124.
- [PMID:10950015] . Pilonidal cyst: cause and treatment. Dis Colon Rectum. 2000;43(8):1146–1156.
- et al. Comparison of three methods in surgical treatment of pilonidal disease. ANZ J Surg. 2001;71(6):362–364. [PMID:11409022] , , ,
- et al. Endoscopic pilonidal sinus treatment: a prospective multicentre trial. Colorectal Dis. 2016;18(5):O164–O170. [PMID:26946340] , , ,
CODES
ICD10
- L05.91 Pilonidal cyst without abscess
- L05.92 Pilonidal sinus without abscess
- L05.01 Pilonidal cyst with abscess
- L05.02 Pilonidal sinus with abscess
SNOMED
- 432863009 pilonidal disease (disorder)
- 47639008 cyst - pilonidal (disorder)
- 85224001 pilonidal cyst with abscess (disorder)
- 311453002 Pilonidal sinus of natal cleft
- 76545008 pilonidal cyst without abscess (disorder)
- 200715006 Pilonidal sinus without abscess
- 431709001 Pilonidal abscess of natal cleft
CLINICAL PEARLS
- Avoid prolonged sitting.
- Lose weight.
- Trim hair in gluteal cleft weekly.
- Refer recurring infections for more definitive surgical management.
Last Updated: 2026
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