Medical Marijuana

Medical Marijuana is a topic covered in the 5-Minute Clinical Consult.

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Basics

Medical marijuana refers to the use of cannabis or cannabinoids as medical therapy to treat disease or alleviate symptoms.

Description

  • Marijuana contains approximately 60 pharmacologically active compounds (“cannabinoids”).
  • The exact compounds and mechanisms of action of the cannabinoids in marijuana is an area of ongoing research.
  • The most commonly isolated active ingredients include Δ-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). Most of the psychoactive properties come from THC.
  • Routes of administration include inhaled, intranasal, oral (extract, mixed into food, or made into tea), sublingual, and topical.
  • Cannabinoids can be taken in herbal form, extracted naturally from the plant, gained by isomerization of CBD, or manufactured synthetically.

Epidemiology

  • Cannabis is the most widely consumed illicit substance worldwide.
  • An estimated 178 million people aged 15 to 64 years used cannabis at least once in 2012.
  • In the United States in 2010, 6.9% of individuals 12 years old had smoked cannabis in the previous month, and it is estimated that 25% of the American population has used it at least once.
  • Use among high school seniors now exceeds tobacco use (32% vs. 25%).
  • In the United States, as of 2016, 30 states and Washington, DC had introduced laws to permit the medical use of cannabis.
  • Under federal law, marijuana remains a schedule 1 substance.

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Citation

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TY - ELEC T1 - Medical Marijuana ID - 1688032 ED - Baldor,Robert A, ED - Domino,Frank J, ED - Golding,Jeremy, ED - Stephens,Mark B, BT - 5-Minute Clinical Consult, Updating UR - https://im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/1688032/all/Medical_Marijuana PB - Wolters Kluwer ET - 27 DB - Medicine Central DP - Unbound Medicine ER -