Pancreatitis, Chronic

Pancreatitis, Chronic is a topic covered in the 5-Minute Clinical Consult.

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  • Long-standing and progressive destruction of pancreatic tissue due to persistent inflammation
  • Results in exocrine and/or endocrine insufficiency
  • Major features
    • Pain
    • Malabsorption
    • Diabetes mellitus (type 3)
    • Increased risk of pancreatic cancer



Predominant age: 35 to 45 years (usually related to alcohol abuse)

  • Predominant sex: male > female
  • Hospitalization more common for blacks than whites


Hereditary pancreatitis is a rare condition with an autosomal dominant inheritance pattern; mutations in PRSS1 gene and SPINKI gene

General Prevention

  • Avoid tobacco.
  • Avoid excess alcohol.

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* When formatting your citation, note that all book, journal, and database titles should be italicized* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Pancreatitis, Chronic ID - 117286 ED - Baldor,Robert A, ED - Domino,Frank J, ED - Golding,Jeremy, ED - Stephens,Mark B, BT - 5-Minute Clinical Consult, Updating UR - PB - Wolters Kluwer ET - 27 DB - Medicine Central DP - Unbound Medicine ER -