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Premature destruction of RBCs, either intravascularly or extravascularly, leading to a shortened red cell survival time. The premature destruction can be caused by intrinsic factors (defects within the RBC itself) or extrinsic factors (factors outside the RBC leads to premature destruction).
Incidence depends on the cause of hemolysis.
Acquired (extrinsic) disorders | Hereditary (intrinsic) disorders |
---|---|
Infectious | Hemoglobinopathies |
Drug induced | RBC membrane defects |
Immune mediated | RBC enzyme defects |
Microangiopathic |
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Premature destruction of RBCs, either intravascularly or extravascularly, leading to a shortened red cell survival time. The premature destruction can be caused by intrinsic factors (defects within the RBC itself) or extrinsic factors (factors outside the RBC leads to premature destruction).
Incidence depends on the cause of hemolysis.
Acquired (extrinsic) disorders | Hereditary (intrinsic) disorders |
---|---|
Infectious | Hemoglobinopathies |
Drug induced | RBC membrane defects |
Immune mediated | RBC enzyme defects |
Microangiopathic |
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