Acute tubular necrosis

Etiology

Toxins: NSAIDs, antibiotics, contrast, multiple myeloma, rhabdomyolysis, hemolysis, chemotherapy, hyperuricemia, cyclosporine
Ischemia, e.g., prolonged prerenal azotemia

DDx

Prerenal azotemia, eg, dehydration
Postrenal azotemia, eg, benign prostatic hyperplasia
Other renal causes of acute renal failure
- Acute glomerulonephritis: immune complex (eg, IgA nephropathy), pauci-immune (eg, Wegener’s granulomatosis), anti-GBM disease
- Acute interstitial nephritis: drugs (eg, β-lactams), infections (eg, Streptococcus), immune (eg, systemic lupus erythematosus)

See related DDx

Acute renal failure

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