Pancytopenia
Etiology
Etiology
Etiology
Bone marrow disorders
- Aplastic anemia
- Myelodysplastic syndrome
- Acute leukemia
- Myelofibrosis
- Infiltrative disease: lymphoma, myeloma, carcinoma, hairy cell leukemia
- Megaloblastic anemia
- Paroxysmal nocturnal hemoglobinuria
- Bone marrow irradiation
- Genetic, e.g., Fanconi’s anemia
Nonmarrow disorders - Hypersplenism
- Systemic lupus erythematosus
- Infection: tuberculosis, AIDS, leishmaniasis, brucellosis, histoplasmosis. (Viruses causing aplastic anemia: hepatitis, Epstein-Barr virus, HIV, parvovirus B19)
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