Lower extremity edema

DDx

Cardiovascular

  • Congestive heart failure (CHF) (right-sided)
  • Pericardial effusion
  • Pericarditis
  • Tricuspid regurgitation
  • Tricuspid stenosis
  • Pulmonic stenosis
  • Cor pulmonale
  • Venous insufficiency (most common)
  • Venous obstruction
Noncardiovascular
  • Cirrhosis
  • Low albumin (nephrotic syndrome, malnutrition, protein-losing enteropathy)
  • Cellulitis
  • Premenstrual fluid retention
  • Drugs (vasodilators, eg, calcium channel blockers, salt-retaining medications, eg, NSAIDs, thiazolidinediones)
  • Musculoskeletal (Baker’s cyst, gastrocnemius tear, compartment syndrome)
  • Lymphatic obstruction
  • Preeclampsia-eclampsia
  • Myxedema
  • Lymphatic filariasis
  • Eosinophilic fasciitis

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