Bone pain & pathologic fractures

DDx

• Osteoporosis (fracture)
• Malignancy, primary or metastatic (fracture)
• Hyperparathyroidism (bone pain)
• Hyperthyroidism (osteopenia)
• Cushing’s syndrome (osteopenia)
• Osteogenesis imperfecta (fracture)
• Osteomalacia or rickets (bowing and pseudofractures)
• Multiple myeloma (bone pain, fracture)
• Paget’s disease (bone pain)
• Leukemia (bone pain)
• Gaucher disease (fracture)
• Beta thalassemia (fracture)