Lactic acidosis

Etiology

Tissue hypoxia, eg, cardiogenic, septic, or hemorrhagic shock; seizure; carbon monoxide or cyanide poisoning
Hepatic or renal failure
Intestinal ischemia
Diabetes, especially with metformin use
Ketoacidosis
Infection
Leukemia or lymphoma
Drugs: ethanol, methanol, salicylates, isoniazid
AIDS
Idiopathic

See related DDx

Metabolic acidosis, increased anion gap

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