Acute monoarthritis

DDx

Don’t miss

  • Septic arthritis

Inflammatory

  • Infection, eg, Staphylococcus aureus septic arthritis, gonococcal arthritis, endocarditis, parvovirus B19
  • Crystal-induced, eg, gout, pseudogout
  • Reactive arthritis (Reiter’s syndrome)
  • Uncommon: other seronegative spondyloarthropathy, connective tissue disease

Noninflammatory

  • Trauma
  • Nontraumatic bleed, eg, coagulopathy
  • Sickle cell crisis

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