Acromegaly most commonly presents between the ages of 40 and 45 years, but the diagnosis is typically delayed for 7 to 10 years after the onset of symptoms.
3 cases per million persons per year
60 to 480 cases per million persons
There are currently no preventive strategies for this condition.
Follow-Up Tests & Special Considerations
If the sellar MRI is normal, perform a CT scan of the chest and abdomen to evaluate for extrapituitary source of acromegaly. Plasma GHRH should also be measured using a diagnostic threshold of 250 to 300 ng/L (1)[B].
A multidisciplinary team experienced in managing pituitary tumors is essential for treatment.
Pharmacologic treatment is generally used if inadequate response to surgery or poor surgical candidate:
Monitoring for medical and surgical treatment:
Pituitary Patient Resource Guide, published by the Pituitary Network Association (www.acromegaly.org)
See section on “Commonly Associated Conditions.”
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