MEDLINE Journals

    Prevalence, incidence and geographical distribution of Toxoplasma gondii antibodies in pregnant women in Denmark.

    Authors
    Lebech M, Larsen SO, Petersen E 
    Source
    Scand J Infect Dis 1993; 25(6) :751-6.
    Abstract

    The purpose of this study was to determine the prevalence and incidence of toxoplasmosis in pregnant women in Denmark, and to estimate the incidence of congenital toxoplasmosis. Consecutive serum samples from 5,402 women were analysed for specific IgG and IgM Toxoplasma gondii antibodies by EIA. The prevalence of IgG antibodies was 27.4%. The seroconversion rate was estimated to be 1.16% per year (SE = 0.0017) in all age groups, consistent with an incidence of acute toxoplasmosis in pregnant women of 0.65%. Specific IgM antibodies were present in sera from 29 women. Based on an assumed maternofetal transmission rate of 50%, the incidence of congenital toxoplasmosis was estimated to be 0.33%. Based on these data it is predicted that about 410 pregnant women are infected with T. gondii every year in Denmark, and that about 200 children every year are infected in utero by T. gondii. There was no difference in the prevalence of antibodies in women from rural or urban areas, or from different parts of Denmark.

    Mesh
    Adolescent
    Adult
    Animals
    Antibodies, Protozoan
    Cross-Sectional Studies
    Data Interpretation, Statistical
    Denmark
    Female
    Humans
    Immunoglobulin G
    Immunoglobulin M
    Incidence
    Middle Aged
    Pregnancy
    Pregnancy Complications, Parasitic
    Prevalence
    Retrospective Studies
    Rural Health
    Seroepidemiologic Studies
    Toxoplasma
    Toxoplasmosis
    Toxoplasmosis, Congenital
    Urban Health
    Language

    eng

    Pub Type(s)
    Journal Article
    PubMed ID

    8052816

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